Human molecular genetics /
Strachan, T.,
Human molecular genetics / - 5th edition. - xiii, 770 pages : colour illustrations ; 29 cm.
Includes bibliographical references and index.
Preface -- About the authors -- Contributors -- Basic principles of nucleic acid structure and gene expression -- Fundamentals of cells and chromosomes -- Fundamentals of cell-cell interactions and immune system biology -- Aspects of early mammalian development, cell differentiation, and stem cells -- Patterns of inheritance -- Core DNA technologies: amplifying DNA, nucleic acid hybridization, and DNA sequencing -- Analyzing the structure and expression of genes and genomes -- Principles of genetic manipulation of mammalian cells -- Uncovering the architecture and workings of the human genome -- Gene regulation and the epigenome -- An overview of human genetic variation -- Human population genetics -- Comparative genomics and genome evolution -- Human evolution -- Chromosomal abnormalities and structural variants -- Moleculars pathology: connecting phenotypes to genotypes -- Mapping and identifying genes for monogenic disorders -- Complex disease identifying susceptibility factors and understanding pathogenesis -- Cancer genetics and genomics -- Genetic testing in healthcare and the law -- Model organisms and modeling disease -- Genetic approaches to treating disease.
This work provides guidance on the principles underlying modern human molecular genetics. This new edition has been updated to take account of the changes in our understanding of this field since the late 1990s.
9780815345893 9780815345893: £62.99 0815345895 0367002507 9780367002503
Human molecular genetics.
Genome, Human.
Molecular Biology.
611.01816 / STR
Human molecular genetics / - 5th edition. - xiii, 770 pages : colour illustrations ; 29 cm.
Includes bibliographical references and index.
Preface -- About the authors -- Contributors -- Basic principles of nucleic acid structure and gene expression -- Fundamentals of cells and chromosomes -- Fundamentals of cell-cell interactions and immune system biology -- Aspects of early mammalian development, cell differentiation, and stem cells -- Patterns of inheritance -- Core DNA technologies: amplifying DNA, nucleic acid hybridization, and DNA sequencing -- Analyzing the structure and expression of genes and genomes -- Principles of genetic manipulation of mammalian cells -- Uncovering the architecture and workings of the human genome -- Gene regulation and the epigenome -- An overview of human genetic variation -- Human population genetics -- Comparative genomics and genome evolution -- Human evolution -- Chromosomal abnormalities and structural variants -- Moleculars pathology: connecting phenotypes to genotypes -- Mapping and identifying genes for monogenic disorders -- Complex disease identifying susceptibility factors and understanding pathogenesis -- Cancer genetics and genomics -- Genetic testing in healthcare and the law -- Model organisms and modeling disease -- Genetic approaches to treating disease.
This work provides guidance on the principles underlying modern human molecular genetics. This new edition has been updated to take account of the changes in our understanding of this field since the late 1990s.
9780815345893 9780815345893: £62.99 0815345895 0367002507 9780367002503
Human molecular genetics.
Genome, Human.
Molecular Biology.
611.01816 / STR