Drug delivery : principles and applications /
By: Wang, Binghe.
Contributor(s): Siahaan, Teruna | Soltero, Richard.
Publisher: Hoboken, N.J. : Wiley-Interscience, c2005Description: xi, 448 p. : ill. ; 23 cm.Content type: text Media type: unmediated Carrier type: volumeISBN: 9780471474890 (cloth); 9780471474890:.Subject(s): Drug delivery systems | Pharmaceutical chemistryDDC classification: 615.6Item type | Current library | Call number | Copy number | Status | Date due | Barcode | Item holds |
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Standard Loan | ATU Sligo Yeats Library Main Lending Collection | 615.6 WAN (Browse shelf(Opens below)) | 1 | Available | 0058503 |
Includes bibliographical references and index.
Factors that impact the developability of drug candidates: an overview / Chao Han and Binghe Wang -- Physiological, biochemical, and chemical barriers to oral drug delivery / Anna Maria Calcagno and Teruna J. Siahaan -- Pathways for drug delivery to the central nervous system / Yan Zhang and Donald W. Miller -- Physiochemical properties, formulation, and drug delivery / Dewey H. Barich, Mark T. Zell, and Eric J. Munson -- Targeted bioavailability: a fresh look at pharmacokinetic and pharmacodynamic issues in drug delivery / William F. Elmquist -- Presystemic and first-pass metabolism / W. Griffith Humphreys -- Cell culture models for drug transport studies / D. Nedra Karunaratne...[et al. -- Prodrug approaches to drug delivery / Longqin Hu -- Receptor-mediated drug delivery / Christopher P. Leamon and Philip S. Low -- Oral Protein and peptide drug delivery / Rick Soltero -- Metabolic activation and drug targeting / Xiangming Guan -- Ultrasound-mediated drug delivery / Ka-yun Ng and Terry O. Matsunaga -- Polycationic peptides and proteins in drug delivery: focus on nonclassical transport / Lisa A. Kueltzo and C. Russell Middaugh -- Gene therapy and gene delivery / Naoki Kobayashi, Makia Nishikawa, and Yoshinobu Takakura -- Parenteral formulation for peptides, proteins, and monoclonal antibodies drugs: a commercial development overview / John A. Bontempo -- Pulmonary drug delivery: pharmaceutical chemistry and aerosol technology / Anthony J. Hickey -- Antibody-directed drug delivery / Hervé Le Calvez...[et al.] -- Efflux transporters in drug excretion / Shuzhong Zhang and Marilyn E. Morris -- Liposomes as drug delivery vehicles / Guijun Wang -- Regulatory and intellectual property issues in drug delivery research / Shihong Nicolaou.
More than 50% of drugs that are developed cannot be adequately delivered to the desired target. This book covers an increasingly important area of pharmaceutical research.