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Drug delivery : principles and applications /

By: Wang, Binghe.
Contributor(s): Siahaan, Teruna | Soltero, Richard.
Publisher: Hoboken, N.J. : Wiley-Interscience, c2005Description: xi, 448 p. : ill. ; 23 cm.Content type: text Media type: unmediated Carrier type: volumeISBN: 9780471474890 (cloth); 9780471474890:.Subject(s): Drug delivery systems | Pharmaceutical chemistryDDC classification: 615.6
Contents:
Factors that impact the developability of drug candidates: an overview / Chao Han and Binghe Wang -- Physiological, biochemical, and chemical barriers to oral drug delivery / Anna Maria Calcagno and Teruna J. Siahaan -- Pathways for drug delivery to the central nervous system / Yan Zhang and Donald W. Miller -- Physiochemical properties, formulation, and drug delivery / Dewey H. Barich, Mark T. Zell, and Eric J. Munson -- Targeted bioavailability: a fresh look at pharmacokinetic and pharmacodynamic issues in drug delivery / William F. Elmquist -- Presystemic and first-pass metabolism / W. Griffith Humphreys -- Cell culture models for drug transport studies / D. Nedra Karunaratne...[et al. -- Prodrug approaches to drug delivery / Longqin Hu -- Receptor-mediated drug delivery / Christopher P. Leamon and Philip S. Low -- Oral Protein and peptide drug delivery / Rick Soltero -- Metabolic activation and drug targeting / Xiangming Guan -- Ultrasound-mediated drug delivery / Ka-yun Ng and Terry O. Matsunaga -- Polycationic peptides and proteins in drug delivery: focus on nonclassical transport / Lisa A. Kueltzo and C. Russell Middaugh -- Gene therapy and gene delivery / Naoki Kobayashi, Makia Nishikawa, and Yoshinobu Takakura -- Parenteral formulation for peptides, proteins, and monoclonal antibodies drugs: a commercial development overview / John A. Bontempo -- Pulmonary drug delivery: pharmaceutical chemistry and aerosol technology / Anthony J. Hickey -- Antibody-directed drug delivery / Hervé Le Calvez...[et al.] -- Efflux transporters in drug excretion / Shuzhong Zhang and Marilyn E. Morris -- Liposomes as drug delivery vehicles / Guijun Wang -- Regulatory and intellectual property issues in drug delivery research / Shihong Nicolaou.
Summary: More than 50% of drugs that are developed cannot be adequately delivered to the desired target. This book covers an increasingly important area of pharmaceutical research.
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Holdings
Item type Current library Call number Copy number Status Date due Barcode Item holds
Standard Loan Standard Loan ATU Sligo Yeats Library Main Lending Collection 615.6 WAN (Browse shelf(Opens below)) 1 Available 0058503
Total holds: 0

Includes bibliographical references and index.

Factors that impact the developability of drug candidates: an overview / Chao Han and Binghe Wang -- Physiological, biochemical, and chemical barriers to oral drug delivery / Anna Maria Calcagno and Teruna J. Siahaan -- Pathways for drug delivery to the central nervous system / Yan Zhang and Donald W. Miller -- Physiochemical properties, formulation, and drug delivery / Dewey H. Barich, Mark T. Zell, and Eric J. Munson -- Targeted bioavailability: a fresh look at pharmacokinetic and pharmacodynamic issues in drug delivery / William F. Elmquist -- Presystemic and first-pass metabolism / W. Griffith Humphreys -- Cell culture models for drug transport studies / D. Nedra Karunaratne...[et al. -- Prodrug approaches to drug delivery / Longqin Hu -- Receptor-mediated drug delivery / Christopher P. Leamon and Philip S. Low -- Oral Protein and peptide drug delivery / Rick Soltero -- Metabolic activation and drug targeting / Xiangming Guan -- Ultrasound-mediated drug delivery / Ka-yun Ng and Terry O. Matsunaga -- Polycationic peptides and proteins in drug delivery: focus on nonclassical transport / Lisa A. Kueltzo and C. Russell Middaugh -- Gene therapy and gene delivery / Naoki Kobayashi, Makia Nishikawa, and Yoshinobu Takakura -- Parenteral formulation for peptides, proteins, and monoclonal antibodies drugs: a commercial development overview / John A. Bontempo -- Pulmonary drug delivery: pharmaceutical chemistry and aerosol technology / Anthony J. Hickey -- Antibody-directed drug delivery / Hervé Le Calvez...[et al.] -- Efflux transporters in drug excretion / Shuzhong Zhang and Marilyn E. Morris -- Liposomes as drug delivery vehicles / Guijun Wang -- Regulatory and intellectual property issues in drug delivery research / Shihong Nicolaou.

More than 50% of drugs that are developed cannot be adequately delivered to the desired target. This book covers an increasingly important area of pharmaceutical research.

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