Analytical techniques for clinical chemistry : methods and applications /
Contributor(s): Caroli, Sergio | Záray, Gyula.
Publisher: Hoboken : Wiley, 2012Description: xxx, 800 p. : ill. ; 15 cm.Content type: text Media type: unmediated Carrier type: volumeISBN: 9780470445273:.Subject(s): Clinical chemistry -- Analysis | Biochemistry | Medical industryDDC classification: 616.0756Item type | Current library | Call number | Copy number | Status | Date due | Barcode | Item holds |
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Standard Loan | ATU Sligo Yeats Library Main Lending Collection | 616.0756 CAR (Browse shelf(Opens below)) | 1 | Available | 0078598 |
Includes index, appendices and bibliographic references.
Exploring fundamentals -- Good clinical practice principles: legal background and applicability -- Clinical chemistry and the quest for quality -- Uncertainty in clinical chemistry measurements including preanalytical variables -- The role and significance of reference values in the identification and evaluation of trace elements from diet -- Sample collection, storage, and pretreatment in clinical chemistry -- Metal toxicology in clinical, forensic, and chemical pathology -- Selected applications. elemental speciation in clinical sciences -- The role of analytical chemistry in the safety of drug therapy -- Analytical techniques and quality control of pharmaceuticals -- Detection of drugs in biological fluids for antidoping control -- The applicability of plasma-based techniques to biological monitoring -- Atomic spectrometric techniques for the analysis of clinical samples -- Applications of ICP-MS in human biomonitoring studies -- Molybdenum in biological samples and clinical significance of serum molybdenum -- Application of organometallic speciation in clinical studies -- Biosensors for drug analysis -- Bioimaging of metals and proteomic studies of clinical samples by Laser Ablation Inductively Coupled Plasma Mass Spectrometry (LA-ICP-MS) -- Applications of LC-MS/MS in clinical laboratory diagnostics -- Metabolomics using UPLC/HPLC-Tandem Mass Spectrometry in diagnosis and research of inherited metabolic diseases -- Biomarkers of oxidative stress in plasma and urine -- The use of x-ray techniques in medical research -- Future trends -- A new tool based on the use of stable isotopes and Isotope Pattern Deconvolution (IPD)-ICP-MS for nutritional and clinical studies -- Breath analysis: analytical methodologies and clinical spplications -- Proteo-Metabolomic strategies in the future of drug development -- Basics in laboratory medicine: past, present, and future.
This resource details the role played by analytical techniques in clinical research, from fundamental studies to practical applications. The chapters report on the progress made in developing fit-for-purpose instrumentation, and identify continuing challenges for laboratory analytical techniques.