Includes bibliographical references and index.

Historical perspective : origin to recognition -- Exercise and responses of biologic systems -- Nervous system and movement -- Skeletal-articular system -- Muscular system : structural and functional plasticity -- Muscular system : the control of muscle mass -- Muscular system : fatigue processes -- Autonomic nervous system -- Respiratory system -- Cardiovascular system : design and control -- Cardiovascular system : cardiac function -- Organization and control of circulation to skeletal muscle -- Gastrointestinal system -- Metabolic systems : control of ATP synthesis in skeletal muscle -- Metabolic systems : carbohydrate metabolism -- Metabolic systems : lipid metabolism -- Metabolic systems : interaction of lipid and carbohydrate metabolism -- Metabolic systems : protein and amino acid metabolism in muscle -- Mitochondrial biogenesis induced by endurance training -- Endocrine system : integrated influences on metabolism, growth, and reproduction -- Exercise and the immune system -- Body fluid and hemopoietic systems -- Renal system -- Effects of exercise in altered environments -- Physiologic systems and their responses to conditions of heat and cold -- Physiologic systems and their responses to hypoxia -- Physiologic systems and their responses to conditions of hyperbaria -- Physiologic systems and their responses to conditions of microgravity and bed rest -- Genomics in the future of exercise physiology -- Exercise genomics and proteomics.

Written by international experts in physiology, exercise physiology, and research, this work gives students an advanced level of understanding of exercise physiology. It emphasizes the chronic effects of exercise on various physiological systems in adults and the integrative nature of these physiological responses.