Includes index.

1 Pharmacokinetics and Pharmacodynamics: The Dynamics of Drug Absorption, Distribution, Action, and Elimination / Iain L. O. Buxton 1 -- 2 Membrane Transporters and Drug Response / Kathleen M. Giacomini, Yuichi Sugiyama 41 -- 3 Drug Metabolism / Frank J. Gonzalez, Robert H. Tukey 71 -- 4 Pharmacogenetics / Mary V. Relling, Kathleen M. Giacomini 93 -- 5 The Science of Drug Therapy / John A. Oates 117 -- Section II Drugs Acting at Synaptic and Neuroeffector Junctional Sites 137 -- 6 Neurotransmission: The Autonomic and Somatic Motor Nervous Systems / Thomas C. Westfall, David P. Westfall 137 -- 7 Muscarinic Receptor Agonists and Antagonists / Joan Heller Brown, Palmer Taylor 183 -- 8 Anticholinesterase Agents / Palmer Taylor 201 -- 9 Agents Acting at the Neuromuscular Junction and Autonomic Ganglia / Palmer Taylor 217 -- 10 Adrenergic Agonists and Antagonists / Thomas C. Westfall, David P. Westfall 237 -- 11 5-Hydroxytryptamine (Serotonin): Receptor Agonists and Antagonists / Elaine Sanders-Bush, Steven E. Mayer 297 -- Section III Drugs Acting on the Central Nervous System 317 -- 12 Neurotransmission and the Central Nervous System / Floyd E. Bloom 317 -- 13 General Anesthetics / Alex S. Evers, C. Michael Crowder, Jeffrey R. Balser 341 -- 14 Local Anesthetics / William A. Catterall, Ken Mackie 369 -- 15 Therapeutic Gases: Oxygen, Carbon Dioxide, Nitric Oxide, and Helium / Brett A. Simon, Eric J. Moody, Roger A. Johns 387 -- 16 Hypnotics and Sedatives / Dennis S. Charney, S. John Mihic, R. Adron Harris 401 -- 17 Drug Therapy of Depression and Anxiety Disorders / Ross J. Baldessarini 429 -- 18 Pharmacotherapy of Psychosis and Mania / Ross J. Baldessarini, Frank I. Tarazi 461 -- 19 Pharmacotherapy of the Epilepsies / James O. McNamara 501 -- 20 Treatment of Central Nervous System Degenerative Disorders / David G. Standaert, Anne B. Young 527 -- 21 Opioid Analgesics / Howard B. Gutstein, Huda Akil 547 -- 22 Ethanol / Michael F. Fleming, S. John Mihic, R. Adron Harris 591 -- 23 Drug Addiction and Drug Abuse / Charles P. O'Brien 607 -- Section IV Autacoids: Drug Therapy of Inflammation 629 -- 24 Histamine, Bradykinin, and Their Antagonists / Randal A. Skidgel, Ervin G. Erdos 629 -- 25 Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor / Emer M. Smyth, Anne Burke, Garret A. FitzGerald 653 -- 26 Analgesic-Antipyretic Agents; Pharmacotherapy of Gout / Anne Burke, Emer M. Smyth, Garret A. FitzGerald 671 -- 27 Pharmacotherapy of Asthma / Bradley J. Undem 717 -- Section V Drugs Affecting Renal and Cardiovascular Function 737 -- 28 Diuretics / Edwin K. Jackson 737 -- 29 Vasopressin and Other Agents Affecting the Renal Conservation of Water / Edwin K. Jackson 771 -- 30 Renin and Angiotensin / Edwin K. Jackson 789 -- 31 Treatment of Myocardial Ischemia / Thomas Michel 823 -- 32 Therapy of Hypertension / Brian B. Hoffman 845 -- 33 Pharmacotherapy of Congestive Heart Failure / Thomas P. Rocco, James C. Fang 869 -- 34 Antiarrhythmic Drugs / Dan M. Roden 899 -- 35 Drug Therapy for Hypercholesterolemia and Dyslipidemia / Robert W. Mahley, Thomas P. Bersot 933 -- Section VI Drugs Affecting Gastrointestinal Function 967 -- 36 Pharmacotherapy of Gastric Acidity, Peptic Ulcers, and Gastroesophageal Reflux Disease / Willemijntje A. Hoogerwerf, Pankaj Jay Pasricha 967 -- 37 Treatment of Disorders of Bowel Motility and Water Flux; Antiemetics; Agents Used in Biliary and Pancreatic Disease / Pankaj Jay Pasricha 983 -- 38 Pharmacotherapy of Inflammatory Bowel Disease / Joseph H. Sellin, Pankaj Jay Pasricha 1009 -- Section VII Chemotherapy of Parasitic Infections 1021 -- 39 Chemotherapy of Protozoal Infections: Malaria / Theresa A. Shapiro, Daniel E. Goldberg 1021 -- 40 Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections / Margaret A. Phillips, Samuel L. Stanley, Jr. 1049 -- 41 Chemotherapy of Helminth Infections / Alex Loukas, Peter J. Hotez 1073 -- Section VIII Chemotherapy of Microbial Diseases 1095 -- 42 General Considerations of Antimicrobial Therapy / Henry F. Chambers 1095 -- 43 Sulfonamides, Trimethoprim-Sulfamethoxazole, Quinolones, and Agents for Urinary Tract Infections / William A. Petri, Jr. 1111 -- 44 Penicillins, Cephalosporins, and Other [beta]-Lactam Antibiotics / William A. Petri, Jr. 1127 -- 45 Aminoglycosides / Henry F. Chambers 1155 -- 46 Protein Synthesis Inhibitors and Miscellaneous Antibacterial Agents / Henry F. Chambers 1173 -- 47 Chemotherapy of Tuberculosis, Mycobacterium avium Complex Disease, and Leprosy / William A. Petri, Jr. 1203 -- 48 Antifungal Agents / John E. Bennett 1225 -- 49 Antiviral Agents (Nonretroviral) / Frederick G. Hayden 1243 -- 50 Antiretroviral Agents and Treatment of HIV Infection / Charles Flexner 1273 -- Section IX Chemotherapy of Neoplastic Diseases 1315 -- 51 Antineoplastic Agents / Bruce A. Chabner, Philip C. Amrein, Brian Druker, M. Dror Michaelson, Constantine S. Mitsiades, Paul E. Goss, David P. Ryan, Sumant Ramachandra, Paul G. Richardson, Jeffrey G. Supko, Wyndham H. Wilson 1315 -- Section X Immunomodulators 1405 -- 52 Immunosuppressants, Tolerogens, and Immunostimulants / Alan M. Krensky, Flavio Vincenti, William M. Bennett 1405 -- Section XI Drugs Acting on the Blood and the Blood-Forming Organs 1433 -- 53 Hematopoietic Agents: Growth Factors, Minerals, and Vitamins / Kenneth Kaushansky, Thomas J. Kipps 1433 -- 54 Blood Coagulation and Anticoagulant, Thrombolytic, and Antiplatelet Drugs / Philip W. Majerus, Douglas M. Tollefsen 1467 -- Section XII Hormones and Hormone Antagonists 1489 -- 55 Pituitary Hormones and Their Hypothalamic Releasing Factors / Keith L. Parker, Bernard P. Schimmer 1489 -- 56 Thyroid and Antithyroid Drugs / Alan P. Farwell, Lewis E. Braverman 1511 -- 57 Estrogens and Progestins / David S. Loose, George M. Stancel 1541 -- 58 Androgens / Peter J. Snyder 1573 -- 59 Adrenocorticotropic Hormone; Adrenocortical Steroids and Their Synthetic Analogs; Inhibitors of the Synthesis and Actions of Adrenocortical Hormones / Bernard P. Schimmer, Keith L. Parker 1587 -- 60 Insulin, Oral Hypoglycemic Agents, and the Pharmacology of the Endocrine Pancreas / Stephen N. Davis 1613 -- 61 Agents Affecting Mineral Ion Homeostasis and Bone Turnover / Peter A. Friedman 1647 -- Section XIII Dermatology 1679 -- 62 Dermatological Pharmacology / Lindy P. Fox, Hans F. Merk, David R. Bickers 1679 -- Section XIV Ophthalmology 1707 -- 63 Ocular Pharmacology / Jeffrey D. Henderer, Christopher J. Rapuano 1707 -- Section XV Toxicology 1739 -- 64 Principles of Toxicology and Treatment of Poisoning / Curtis D. Klaassen 1739 -- 65 Heavy Metals and Heavy-Metal Antagonists / Curtis D. Klaassen 1753 -- I Principles of Prescription Order Writing and Patient Compliance / Iain L. O. Buxton 1777 -- II Design and Optimization of Dosage Regimens; Pharmacokinetic Data / Kenneth E. Thummel, Danny D. Shen, Nina Isoherranen, Helen E. Smith 1787.

The undisputed leader in medical pharmacology, without equal. Reflecting all critical developments in drug action and drug-disease interaction, this is the "desert island" book of all medical pharmacology.