000			03621cam a2200517 i 4500
001			ocn987051883
003			OCoLC
005			20210921181123.0
007			ta
008			170321s20172017enka |rb 001|0 eng
010			_a2017932606
015			_aGBB755080 _2bnb
016	7		_a101710331 _2DNLM
016	7		_a018275949 _2Uk
020			_a9780198749691
020			_a9780198749691: _c£39.99
020			_a0198749694
029	0		_aNLM _b101710331
029	1		_aAU@ _b000059983267
029	1		_aUKMGB _b018275949
035			_a(OCoLC)987051883 _z(OCoLC)980423226 _z(OCoLC)980723561 _z(OCoLC)981043372 _z(OCoLC)981145868 _z(OCoLC)981628619 _z(OCoLC)981780679
040			_aNLM _beng _erda _cNLM _dUKUOY _dOCLCF _dYDX _dBDX _dEYM _dVMY _dSINLB _dNRC _dMOU _dZLM _dOCLCO _dOCLCA _dU3W _dOCLCQ _dOCLCO _dUWW _dOCLCQ _dAU@ _dUKMGB
042			_apcc
082	0	4	_a615.19 _223 _bPAT
100	1		_aPatrick, Graham L., _eauthor.
245	1	3	_aAn introduction to medicinal chemistry /
250			_a6th edition.
264		1	_aOxford, United Kingdom : _bOxford University Press, _c2017.
300			_axxxi, 877 pages : _billustrations _c27 cm.
336			_atext _btxt _2rdacontent
336			_atext _2rdacontent
336			_astill image _2rdacontent
337			_aunmediated _bn _2rdamedia
337			_aunmediated _2rdamedia
338			_avolume _bnc _2rdacarrier
338			_avolume _2rdacarrier
504			_aIncludes appendices, bibliographical references and index.
505	0		_aDrugs and drug targets : an overview -- Protein structure and function -- Enzymes : structure and function -- Receptors : structure and function -- Receptors and signal transduction -- Nucleic acids : structure and function -- Enzymes as drug targets -- Receptors as drug targets -- Nucleic acids as drug targets -- Miscellaneous drug targets -- Pharmacokinetics and related topics -- Case study 1 : statins -- Drug discovery : finding a lead -- Drug design : optimizing target interactions -- Drug design : optimizing access to the target -- Getting the drug to market -- Case study 2 : the design of ACE inhibitors -- Case study 3 : artemisinin and related antimalarial drugs -- Case study 4 : the design of oxamniquine -- Combinatorial and parallel synthesis -- Computers in medicinal chemistry -- Quantitative structure-activity relationships (QSAR) -- Case study 5 : design of a thymidylate synthase inhibitor -- Antibacterial agents -- Antiviral agents -- Anticancer agents -- Cholinergics, anticholinergics, and anticholinesterases -- Drugs acting on the adrenergic nervous system -- The opioid analgesics -- Anti-ulcer agents -- Cardiovascular drugs -- Case study 6 : steroidal anti-inflammatory agents -- Case study 7 : current research into antidepressant agents -- Case study 8 : the design and development of aliskiren -- Case study 9 : factor Xa inhibitors -- Case study 10 : reversible inhibitors of HCV NS3-4A protease -- Appendix 1 : essential amino acids -- Appendix 2 : the standard genetic code -- Appendix 3 : statistical data for QSAR -- Appendix 4 : the action of nerves -- Appendix 5 : microorganisms -- Appendix 6 : trade names and drugs -- Appendix 7 : hydrogen bonding interactions.
520	8		_aProviding an introduction to medicinal chemistry, this resource covers basic principles and background, and describes the general tactics and strategies involved in developing an effective drug.
650		0	_aPharmaceutical chemistry.
650	1	2	_aChemistry, Pharmaceutical.
650	2	2	_aDrug Design.
650	2	2	_aPharmacokinetics.
942			_2ddc _cSG_1 _n0
948			_hNO HOLDINGS IN LQI - 88 OTHER HOLDINGS
999			_c267739 _d267739