Pharmaceutical enzymes /
Pharmaceutical enzymes /
- New York : Marcel Dekker, c1997.
- viii, 401 p. : ill. ; 24 cm.
- Drugs and the pharmaceutical sciences ; v. 84 .
Includes bibliographical references and index.
Pt. 1. Bioavailability of pharmaceutical enzymes -- Biopharmaceuticl aspects of enzyme absorption -- The endothelium monolayer: barrier to enzyme and drug delivery -- Pt. 2. Tailoring of pharmaceutical enzymes -- Enzyme-albumin conjugates: advantages and problems with targeting -- Acyl enzymes as prodrugs -- Molecular modeling of pharmaceutically important targets -- Pt. 3. Biochemical and pharmacological properties -- The cysteine proteinases from the latex of Carica papaya L -- Bromelain -- Hyaluronidase -- Pancreatic enzyme replacement -- I-asparaginase: an essential antineoplastic drug -- Macrophage-targeted glucocerebrosidase: a therapeutically effective enzyme replacement product for Gaucher Disease -- Deoxyribonuclease I -- Therapeutic protein inhibitors of elastase -- Pt. 4. Standardization and methodology -- Good standardization practices -- Assays.
0824793757 (alk. paper) 9780824793753
97015723
Enzymes--Therapeutic use.
Enzymes--Testing.
Technology, Pharmaceutical.
615.35 / LAU
Includes bibliographical references and index.
Pt. 1. Bioavailability of pharmaceutical enzymes -- Biopharmaceuticl aspects of enzyme absorption -- The endothelium monolayer: barrier to enzyme and drug delivery -- Pt. 2. Tailoring of pharmaceutical enzymes -- Enzyme-albumin conjugates: advantages and problems with targeting -- Acyl enzymes as prodrugs -- Molecular modeling of pharmaceutically important targets -- Pt. 3. Biochemical and pharmacological properties -- The cysteine proteinases from the latex of Carica papaya L -- Bromelain -- Hyaluronidase -- Pancreatic enzyme replacement -- I-asparaginase: an essential antineoplastic drug -- Macrophage-targeted glucocerebrosidase: a therapeutically effective enzyme replacement product for Gaucher Disease -- Deoxyribonuclease I -- Therapeutic protein inhibitors of elastase -- Pt. 4. Standardization and methodology -- Good standardization practices -- Assays.
0824793757 (alk. paper) 9780824793753
97015723
Enzymes--Therapeutic use.
Enzymes--Testing.
Technology, Pharmaceutical.
615.35 / LAU