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Pharmaceutical enzymes /

Contributor(s): Lauwers, Albert | Scharpé, Simon, 1944-.
Series: Drugs and the pharmaceutical sciences ; v. 84.Publisher: New York : Marcel Dekker, c1997Description: viii, 401 p. : ill. ; 24 cm.Content type: text Media type: unmediated Carrier type: volumeISBN: 0824793757 (alk. paper); 9780824793753.Subject(s): Enzymes -- Therapeutic use | Enzymes -- Testing | Technology, PharmaceuticalDDC classification: 615.35
Contents:
Pt. 1. Bioavailability of pharmaceutical enzymes -- Biopharmaceuticl aspects of enzyme absorption -- The endothelium monolayer: barrier to enzyme and drug delivery -- Pt. 2. Tailoring of pharmaceutical enzymes -- Enzyme-albumin conjugates: advantages and problems with targeting -- Acyl enzymes as prodrugs -- Molecular modeling of pharmaceutically important targets -- Pt. 3. Biochemical and pharmacological properties -- The cysteine proteinases from the latex of Carica papaya L -- Bromelain -- Hyaluronidase -- Pancreatic enzyme replacement -- I-asparaginase: an essential antineoplastic drug -- Macrophage-targeted glucocerebrosidase: a therapeutically effective enzyme replacement product for Gaucher Disease -- Deoxyribonuclease I -- Therapeutic protein inhibitors of elastase -- Pt. 4. Standardization and methodology -- Good standardization practices -- Assays.
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Holdings
Item type Current library Call number Copy number Status Date due Barcode Item holds
Standard Loan Standard Loan ATU Sligo Yeats Library Withdrawn 615.35 LAU (Browse shelf(Opens below)) 1 Available 0050258
Total holds: 0

Includes bibliographical references and index.

Pt. 1. Bioavailability of pharmaceutical enzymes -- Biopharmaceuticl aspects of enzyme absorption -- The endothelium monolayer: barrier to enzyme and drug delivery -- Pt. 2. Tailoring of pharmaceutical enzymes -- Enzyme-albumin conjugates: advantages and problems with targeting -- Acyl enzymes as prodrugs -- Molecular modeling of pharmaceutically important targets -- Pt. 3. Biochemical and pharmacological properties -- The cysteine proteinases from the latex of Carica papaya L -- Bromelain -- Hyaluronidase -- Pancreatic enzyme replacement -- I-asparaginase: an essential antineoplastic drug -- Macrophage-targeted glucocerebrosidase: a therapeutically effective enzyme replacement product for Gaucher Disease -- Deoxyribonuclease I -- Therapeutic protein inhibitors of elastase -- Pt. 4. Standardization and methodology -- Good standardization practices -- Assays.

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